Small Tangential Flow Ultrafiltration System, 0.1~20L/H

CFF-01 Small Tangential Flow Ultrafiltration System, 0.1~20L/H

It is suitable for small-scale TFF research in biological laboratories, such as biological separation, material concentration and protein solution purification. Small size, exquisite, easy to disassemble.

Brief Introduction of Tangential flow filter (TFF)

Tangential flow filter (TFF), also known as cross flow filter (CFF), refers to the liquid flow direction and filter direction perpendicular to the filter form. Liquid flow creates a shear force on the surface of the filter media, reducing the stacking of the cake layer or gel layer, thus ensuring a stable filtration rate.

According to the trapped particles or molecular size can be divided into microfiltration MF, ultrafiltration UF, nanofiltration NF and reverse osmosis RO. TFF technology is currently widely used in pharmaceutical, biological, chemical, food and beverage and environmental protection industries.

Brief introduction of small tangential flow ultrafiltration system

The small tangential flow ultrafiltration system is a set of TFF devices for laboratory users. It is mainly applied to TFF research of small scale or pilot scale in laboratory. The system uses imported original box-type flat film package, can achieve microfiltration, ultrafiltration, to meet the needs of laboratory diversification.

System applications

Cell collection, cell fluid clarification and filtration, recovery of antibodies or recombinant proteins
Concentration and desalination of proteins, peptides or nucleic acids (DNA / RNA / oligonucleotides)
Remove heat source or impurity molecules in the water, buffer, medium solution, equal volume of continuous dialysis

System Features:

Sample recovery rate is extremely high, and efficiently ensure protein activity
Filtration speed is stable, can be continuous cycle of filtration, the film surface does not form a gel layer
Easy to linear amplification, the maximum reduction time and cost from small scale preparation to large-scale production
Universal stainless-steel fixture, matching the major brands of imported original box-type film package, which can be installed 1 to 3 pieces at the same time
Integrated design, easy to operate, according to different needs to choose the appropriate film fixture, peristaltic pump and film package
Stainless steel stent + raw material tank, siphon feeding, easy for laboratory aseptic continuous operation

Basic Information

Model: CFF-01
Process capacity:0.1-20L/H
Membrane form:1~3 blocks, 0.1 m imported box type flat membrane
Power unit: Precision peristaltic pump 220V, Maximum flow 2L/MIN
Raw material tank: Material AISI 316L, Volume 2L

Stainless steel fixture

Material AISI316L
2 in 2 out sanitary quick interface with mirror polishing internal surface and sand blasting outside surface
Fit 0.1 m imported box type flat membrane, optional brand Millpore, Sartorius and PALL.

Power unit

LONGER peristaltic pump with reliable quality
Maximum flow:2L/MIN
Maximum pressure: 0.3Mpa
Control: Start and stop control, direction control, speed control (0-5V,0-10V,0-, 10KHZ are optional)

Stainless steel bracket + raw material tank

Material AISI 316L
Sartorius Outlet Filter
Siphon feeding, easy lab aseptic continuous operation
Tank volume: 1L, 2L, 3.5L, 5L, 10L, can be customized

Flat membrane packs

Filtration area: 0.1 m2 (CFF-O1) Ultrafiltration / microfiltration is optional
Membrane material: Biomax，PLC(modified cellulose)PVDF (polyvinylidene fluoride)
Optional brand: Millpore, Sartorius, PALL

Membrane material	Molecular weight cut-off (KD)	Most suitable molecular retention range>99%(KD)
Biomax-5	5	12-25(growth factor hormone)
Biomax-8	8	25-50(growth factor, hormone)
Biomax-10	10	50-100(growth factor, hormone)
Biomax-30	30	100-140(enzyme)
Biomax-50	50	140-300(lgGs)
Biomax-100	100	300-500 (parvovirus, antigen)
Biomax-300	300	> 500 (lgMs, big virus)
Biomax-500	500	> 0.3um (colloid, granules)
Biomax-1000	1000	> 0.3um (colloid, granules)
PLCCC	5	8-18(proinsulin, hematopoietic factor)
PLCGC	10	18-60(hemoglobin, enzyme)
PLCTK	30	60-200(monoclonal antibody)
PLCHK	100	200-500(parvovirus, viral antigen)
PLCMK	300	> 500 (lgMs, big virus)
PLCXK	1000	>0.3um(colloid, granules)
PVDF(Microfiltration)	0.1um/0.22um/0.45um/0.65um	Large diameter of the bacteria particles

Specification

Model	CFF-01
Power unit	Precision peristaltic pump 220VMaximum flow 2L/MINSeamless replacement with four plunger diaphragm pumpSpeed range 1-600RPM
Membrane element	Imported box type flat membrane, with an area of 0.1 square meters, can install 1~3 blocks
Process capacity	0.1~20L/H
Stainless steel fixture	Material AISI316Lsanitary quick interface with mirror polishing internal surface and sandblasting outside surfacefit all brands of membrane packs
Raw material tank	Material AISI 316L, volume 2L, Sartorius outlet filter
Stainless steel bracket	Material AISI 316L, sand blasting outside surface
Pressure gauge	Sanitary diaphragm pressure gauge, range 0~4Mpa, anti-shaking pointer

Item no.	Name	Picture
CFF001	Four plunger diaphragm pump High precision pump head imported from Germany Can be upgraded to color touch screen with data exporting functionWith low pulse and quiet operationSimple design and easy cleaning
CFF002	Tank weighing METTLER-TOLEDO original XS series precisionbalanceDigital display and touch screenProvide matching tripod feed tank
CFF003	Fully automatic control system Both CFF-01, CFF-O5 can be upgraded to fully automatic control systemCompact design, easy for laboratory users to use and moveOne-piece modular design, can be customized according to user requirements Pump, pressure, temperature, flow meter and so on, using digital analog signal
CFF004	Fully automatic touch screen control Adopts the latest version of HM-ControlAll the experimental data are monitored, collected and exported in real timeThe device can be connected with PC terminals, mobile phones and iPad through WIFI to realize multi end usersSimultaneous detection and manipulation